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1.
Materials Today Sustainability ; : 100161, 2022.
Article in English | ScienceDirect | ID: covidwho-1867617

ABSTRACT

Advanced building design technology is being proposed to eliminate all pathogens, including COVID-19, inside buildings naturally before they attack the human body. Pathogens comprise viruses, fungi, molds, protozoans, and bacteria that cause deadly diseases in humans. Thus, in this research, the application of solar irradiance through an outer glazing wall of the building forming Ultraviolet Germicidal Irradiation (UVGI) derived from sunlight has been performed to eliminate all pathogens inside the buildings before the pathogens attack the human body to cause deadly disease. Based on the findings that all pathogens, including COVID-19, can be killed with short-range wavelengths of 254-280 UVGI by disrupting their nucleic acid bonds, the pathogens are forced to malfunction in their biochemical functions and eventually the pathogens are caused to die. Simply, utilization of the outer glazing wall of a building to kill pathogens by controlling the photophysical reaction shall indeed be an interesting field of science to eliminate pathogens inside the building before those pathogens penetrate the human body.

2.
Zhongguo Zhong Yao Za Zhi ; 45(7): 1521-1525, 2020 Apr.
Article in Chinese | MEDLINE | ID: covidwho-324708

ABSTRACT

The global outbreak of coronavirus disease 2019(COVID-19) has further spread, and there is an increasing number of confirmed cases in many countries. On February 28, 2020 of Geneva time, the World Health Organization has raised global risk level to the very high level in view of outbreak of COVID-19. Since some patients' condition appeared to deteriorate rapidly after infection of this 2019 novel coronavirus(2019-nCoV), a variety of treatments should be considered. Holistic view and syndrome differentiation are the two characteristics of traditional Chinese medicine(TCM). Therefore, under the guidance of the holistic view, syndrome diffe-rentiation of TCM has achieved good effects in the treatment of COVID-19. This treatment mainly aimed at eliminating pathogens and strengthening overall health, regulating the balance of body and coordinating various of functions of Zangfu organs. In addition, modern medical proposes host-directed therapy(HDT), a strategy aims to interfere with host cell mechanism, enhance immune responses, and reduce exacerbated inflammation. To some extent, the combined application of HDT and antiviral therapy is highly consistent with the therapeutic concept of the holistic view of TCM. Therefore, under the guidance of the holistic view, syndrome differentiation of TCM uses treatments, such as clearing heat, detoxification, relieving asthma, clearing damp and phlegm, together with Lianhua Qingwen Capsules, Maxing Shigan Decoction, and Haoqin Qingdan Decoction under the guidance of these therapeutic methods. These therapeutic methods and prescriptions intervened with both virus and host at the same time in the treatment of COVID-19, which has important implications for the effective clinical treatment of COVID-19.


Subject(s)
Betacoronavirus , Coronavirus Infections/drug therapy , Medicine, Chinese Traditional , Pneumonia, Viral/drug therapy , COVID-19 , Humans , Pandemics , SARS-CoV-2 , COVID-19 Drug Treatment
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